LINKAGE STUDIES IN BARLEY

A Genetic Study of Linkage and Inheritance in Barley

Marker Imputation in Barley Association Studies

Association mapping requires high marker density, potentially leading to many missing marker data and to high genotyping costs. In human genetics, methods exist to impute missing marker data and whole markers typed in a reference panel but not in the experimental dataset. We sought to determine if an imputation method developed for human data would function effectively in a barley (Hordeum vulg...

A simple sequence repeat-based linkage map of barley.

A total of 568 new simple sequence repeat (SSR)-based markers for barley have been developed from a combination of database sequences and small insert genomic libraries enriched for a range of short simple sequence repeats. Analysis of the SSRs on 16 barley cultivars revealed variable levels of informativeness but no obvious correlation was found with SSR repeat length, motif type, or map posit...

Knowledge linkage structures in communication studies

This research analyzes a “who cites whom” matrix in terms of aggregated, journal-journal citations to determine the location of communication studies on the academic spectrum. Using the Journal of Communication as the seed journal, the 2006 data in the Journal Citation Reports are used to map communication studies. The results show that social and experimental psychology journals are the most f...

Assessing genomewide statistical significance in linkage studies.

Assessment of genomewide statistical significance in multipoint linkage analysis is a thorny problem. The existing analytical solutions rely on strong assumptions (i.e., infinitely dense or equally spaced genetic markers that are fully informative and completely observed, and a single type of relative pair) which are rarely satisfied in real human studies, while simulation-based methods are com...